Flights from Columbia to Knoxville
Cheap COU to Knoxville flights
Book your COU to TYS flights with Expedia and find last-minute Columbia to Knoxville airfare. Expedia offers discount airfare on multiple airline carriers that fly direct and indirect routes between COU and TYS, with new flight deals and promotions almost daily. When you book your next trip from Columbia Regional to McGhee Tyson with Expedia, you can rest assured you’re getting great ticket prices and excellent service from one of the world’s most trusted travel providers.
Discount flights from Columbia to Knoxville airfare
Browse the best deals on flights from COU to TYS. Deals are based on recent deals found by other Expedia users like you. Pricing may have changed for individual airlines. Expand the list to see all available flight deals from COU to TYS.
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Last Minute Columbia Flight Deals
Traveling on short notice? Expedia offers great deals on last-minute flights from Columbia Airport to the most popular destinations. Deals are based on recent prices found by other Expedia users within the last 12 hours. Prices change often for individual airlines, so check back regularly!
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Columbia, Missouri (COU) to Knoxville, Tennessee (TYS)
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- Roundtrip (including all taxes and fees)
- Per Adult
- Based on e-ticket purchase
- Shown without coupon discounts
The lowest roundtrip price(s) recently found
Departing From:
| Airport | Flight To | Travel Dates (Nights) |
Hotel Rating | Package Discount |
Price per Passenger |
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Popular Flights from Columbia, Missouri
Browse popular flight destinations from Columbia (COU), and plan your next exciting trip. Expedia has cheap flights from Columbia on multiple airline carriers, so book your next trip today!
Top Columbia Flights to US Destinations
Columbia to Chicago (COU - ORD)
Columbia to New York (COU - JFK)
Columbia to Denver (COU - DEN)
Columbia to Atlanta (COU - ATL)
Columbia to San Francisco (COU - SFO)
Columbia to Miami (COU - MIA)
Columbia to Los Angeles (COU - LAX)
Columbia to Las Vegas (COU - LAS)
Columbia to Houston (COU - IAH)
Columbia to Newark (COU - EWR)
Columbia to New York (COU - JFK)
Columbia to Denver (COU - DEN)
Columbia to Atlanta (COU - ATL)
Columbia to San Francisco (COU - SFO)
Columbia to Miami (COU - MIA)
Columbia to Los Angeles (COU - LAX)
Columbia to Las Vegas (COU - LAS)
Columbia to Houston (COU - IAH)
Columbia to Newark (COU - EWR)
Top Columbia International Destinations
Columbia to San Juan (COU - SJU)
Columbia to Istanbul (COU - SAW)
Columbia to Guam (COU - GUM)
Columbia to Charlotte Amalie (COU - STT)
Columbia to Gerona (COU - GRO)
Columbia to Vieques (COU - VQS)
Columbia to Christiansted (COU - STX)
Columbia to Aguadilla (COU - BQN)
Columbia to San Juan (COU - SIG)
Columbia to Ponce (COU - PSE)
Columbia to Istanbul (COU - SAW)
Columbia to Guam (COU - GUM)
Columbia to Charlotte Amalie (COU - STT)
Columbia to Gerona (COU - GRO)
Columbia to Vieques (COU - VQS)
Columbia to Christiansted (COU - STX)
Columbia to Aguadilla (COU - BQN)
Columbia to San Juan (COU - SIG)
Columbia to Ponce (COU - PSE)
Popular Flights from Knoxville, Tennessee
Browse popular flight destinations from Knoxville (TYS), and plan your next exciting trip. Expedia has cheap flights from Knoxville on multiple airline carriers, so book your next trip today!
Top Knoxville Flights to US Destinations
Knoxville to Chicago (TYS - ORD)
Knoxville to New York (TYS - JFK)
Knoxville to Denver (TYS - DEN)
Knoxville to Atlanta (TYS - ATL)
Knoxville to San Francisco (TYS - SFO)
Knoxville to Miami (TYS - MIA)
Knoxville to Los Angeles (TYS - LAX)
Knoxville to Las Vegas (TYS - LAS)
Knoxville to Houston (TYS - IAH)
Knoxville to Newark (TYS - EWR)
Knoxville to New York (TYS - JFK)
Knoxville to Denver (TYS - DEN)
Knoxville to Atlanta (TYS - ATL)
Knoxville to San Francisco (TYS - SFO)
Knoxville to Miami (TYS - MIA)
Knoxville to Los Angeles (TYS - LAX)
Knoxville to Las Vegas (TYS - LAS)
Knoxville to Houston (TYS - IAH)
Knoxville to Newark (TYS - EWR)
Top Knoxville International Destinations
Knoxville to London (TYS - LHR)
Knoxville to Paris (TYS - CDG)
Knoxville to Amsterdam (TYS - AMS)
Knoxville to London (TYS - LGW)
Knoxville to Barcelona (TYS - BCN)
Knoxville to Dubai (TYS - DXB)
Knoxville to Rome (TYS - FCO)
Knoxville to Hong Kong (TYS - HKG)
Knoxville to Toronto (TYS - YYZ)
Knoxville to Frankfurt (TYS - FRA)
Knoxville to Paris (TYS - CDG)
Knoxville to Amsterdam (TYS - AMS)
Knoxville to London (TYS - LGW)
Knoxville to Barcelona (TYS - BCN)
Knoxville to Dubai (TYS - DXB)
Knoxville to Rome (TYS - FCO)
Knoxville to Hong Kong (TYS - HKG)
Knoxville to Toronto (TYS - YYZ)
Knoxville to Frankfurt (TYS - FRA)
COU to TYS Route Map
Columbia to Knoxville Flights, Stats and Airplanes
Route information for flights from Columbia Regional to McGhee Tyson.
Origin:
Destination:
Distance:
497.19 miles
COU - Columbia Regional Airlines
Browse the the most popular airlines servicing the Columbia (COU) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.
TYS - McGhee Tyson Airlines
Browse the most popular airlines servicing the Knoxville (TYS) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.
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