Cheap Flights from Detroit to Sao Tome Island

Last Minute Deals

Last Minute Deals found within the last 12 hours

Top Vacation Deals

Browse Recent Deals found by other Expedia Users

No results found.

Cheap DTW to Sao Tome Island flights

Book your DTW to TMS flights with Expedia and find last-minute Detroit to Sao Tome Island airfare. Expedia offers discount airfare on multiple airline carriers that fly direct and indirect routes between DTW and TMS, with new flight deals and promotions almost daily. When you book your next trip from Detroit Metropolitan Wayne County to Sao Tome Intl. with Expedia, you can rest assured you’re getting great ticket prices and excellent service from one of the world’s most trusted travel providers.

DTW to TMS Flight Schedule

A $ indicates that Expedia.com offers pricing for these airline's flights on the dates shown. A dot () indicates the airline has an available flight scheduled, but Expedia does not provide online booking at this time.

Popular Flights from Detroit, Michigan

Browse popular flight destinations from Detroit (DTW), and plan your next exciting trip. Expedia has cheap flights from Detroit on multiple airline carriers, so book your next trip today!

Popular Flights from Sao Tome Island, Sao Tome and Principe

Browse popular flight destinations from Sao Tome Island (TMS), and plan your next exciting trip. Expedia has cheap flights from Sao Tome Island on multiple airline carriers, so book your next trip today!

DTW to TMS Route Map