Cheap TUP to Knoxville flights

Book your TUP to TYS flights with Expedia and find last-minute Tupelo to Knoxville airfare. Expedia offers discount airfare on multiple airline carriers that fly direct and indirect routes between TUP and TYS, with new flight deals and promotions almost daily. When you book your next trip from Tupelo Regional to McGhee Tyson with Expedia, you can rest assured you’re getting great ticket prices and excellent service from one of the world’s most trusted travel providers.

TUP to TYS Route Map

Tupelo to Knoxville Flights, Stats and Airplanes

Route information for flights from Tupelo Regional to McGhee Tyson.

Destination:
Distance:
290.39 miles

TUP - Tupelo Regional Airlines

Browse the most popular airlines servicing the Tupelo (TUP) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.

TYS - McGhee Tyson Airlines

Browse the most popular airlines servicing the Knoxville (TYS) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.