Which airline flies the most flights to COU? The top airline carrier flying out of Columbia Regional is American Airlines and they fly over 399 flights every month.
- American Airlines - Columbia (COU) to Chicago (ORD) on 5/4 leaving at 2:00 pm and returning on 5/7 at 7:38 pm for only $304 per person.*
- American Airlines - Columbia (COU) to New York (JFK) on 5/11 leaving at 8:21 am and returning on 5/13 at 1:05 pm for only $376 per person.*
- United - Columbia (COU) to San Francisco (SFO) on 5/11 leaving at 3:30 am and returning on 5/14 at 9:05 pm for only $407 per person.*
*Prices vary and will be updated when you view current flight availability results. Deals displayed here are based on flight pricing and availability as of 04/21/2018 and may change as you get closer to the actual flight date. Deals displayed whose dates are in the past are no longer valid.