Which airline flies the most flights to DSM? The top airline carrier flying out of Des Moines Intl. is Delta Air Lines and they fly over 676 flights every month.
- United - Des Moines (DSM) to San Francisco (SFO) on 11/21 leaving at 4:00 am and returning on 11/24 at 8:36 am for only $356 per person.*
- Delta - Des Moines (DSM) to Charlotte (CLT) on 11/21 leaving at 9:53 am and returning on 11/23 at 2:17 pm for only $366 per person.*
- Aer Lingus - Des Moines (DSM) to Rome (FCO) on 11/21 leaving at 9:20 am and returning on 11/24 at 3:30 pm for only $1,373 per person.*
*Prices vary and will be updated when you view current flight availability results. Deals displayed here are based on flight pricing and availability as of 11/16/2017 and may change as you get closer to the actual flight date. Deals displayed whose dates are in the past are no longer valid.