Which airline flies the most flights to TYS? The top airline carrier flying out of McGhee Tyson is American Airlines and they fly over 987 flights every month.
- Delta - Knoxville (TYS) to Atlanta (ATL) on 5/11 leaving at 1:38 pm and returning on 5/13 at 6:21 am for only $166 per person.*
- American Airlines - Knoxville (TYS) to New York (JFK) on 5/4 leaving at 1:02 pm and returning on 5/6 at 7:08 am for only $230 per person.*
- United - Knoxville (TYS) to Baltimore (IAD) on 5/4 leaving at 7:18 am and returning on 5/6 at 11:15 am for only $242 per person.*
*Prices vary and will be updated when you view current flight availability results. Deals displayed here are based on flight pricing and availability as of 04/21/2018 and may change as you get closer to the actual flight date. Deals displayed whose dates are in the past are no longer valid.